Background: Hepatocellular carcinoma (HCC) pathogenesis involves the alteration of multiple liver-specific metabolic pathways.We systematically profiled cancer- and liver-related classes of metabolites in HCC and adjacent liver tissues and applied supervised machine learning to compare their potential yield for HCC biomarkers.Methods: Tumor and cor
Myocardial perfusion imaging in a case of cardiac strangulation: A novel approach to detect pacemaker-induced ischemia
Cardiac strangulation is a rare phenomenon in children following epicardial pacemaker implantation, caused by compression of the heart and great vessels by the epicardial pacemaker wires.We report a rare case of cardiac strangulation presenting after 8 years of epicardial pacemaker implantation.On routine follow-up, computed tomography angiography
Humanizing of process of education of growing personality: morality and its influence on young people, going in for sports
The different aspects of High Heat Plastic Food Pan Covers humane education of growing personality are considered.61 teenagers take part in research (youths).A questionnaire was conducted for the purpose of determination of priority of values teenagers.Questions, touching sporting activity and everyday-domestic relations, were put in a questionnair
Thermo-diffusion and non-uniform heat source/sink effects on hydromagnetic flow of Cu and TiO2 water - based nanofluid partially filled with a porous medium
The study of nanofluids is important due to its vast public health potential.There exist many biomedical applications for nanofluids including drug delivery, magnetic cell separation, hyperthermia testing, photoablation therapy, biosensor High Heat Plastic Food Pan Covers development, bone-substituting implants, bioimaging, cell labeling, and gene
The transcriptional repressor domain of Gli3 is intrinsically disordered.
The MSM transcription factor Gli3 is acting mainly as a transcriptional repressor in the Sonic hedgehog signal transduction pathway.Gli3 contains a repressor domain in its N-terminus from residue G106 to E236.In this study we have characterized the intracellular structure of the Gli3 repressor domain using a combined bioinformatics and experimental